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STONED SCIENCE: INTERACTIONS BETWEEN THC AND CBD

High Times Magazine is a wealth of information on medical marijuana and CBD.

BJ Schmidt wrote an interesting article on the effects of THC and CBD together. How CBD can take the edge of paranoia and anxiety away from using THC as medication. This is great news for people that want the benefit of THC medicinally but do not want the effects of the “high” that goes along with it.

Read the full article here

 

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Study Shows Nearly half of CBD users stop taking traditional meds!!!

Great article by Maureen Meehan – she wrote in High Times Magazine the following ……

Summarizing what Maureen had to say is that in a survey of over 150,000 members, with 55% of users are women while the men preferred the THC tinctures, that a growing number of patients are finding more relief from CBD products than traditional  Pharma meds!!   Read the entire article here

 

More and more people are finding relief from pain, anxiety, stress, memory, depression and cancers etc from CBD – Keep spreading the word people – It’s growing in popularity and the most important point is that it is working!!  I love plants!!

Baja Hemp Co #naturallyhealing

Meagan & Roxanne

 

 

 

 

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CBD & Parkinson’s

Evidence suggests that cannabis could potentially slow the progression of Parkinson’s by providing neuroprotective effects. The cannabinoids found in cannabis are able to suppress the excitotoxicity, glial activation and oxidative injury that cause the degeneration of the dopamine-releasing neurons. In addition, they improve the function of cell’s mitochondria and activation of cellular debris clearance, further encouraging neuron health 6,7,9,16.

Researchers have found evidence that one specific cannabinoid found in cannabis, tetrahydrocannabinol (THC), helps with  the treatment of Parkinson’s disease by assisting in the prevention of damage caused by free radicals and activating a receptor that encourages the formation of new mitochondria16.

Another major cannabinoid found in cannabis, cannabidiol (CBD), has also demonstrated its ability to support the health of neural cells mitochondria, causing the researchers to conclude that CBD should be considered as a potential therapeutic option in neurodegenerative disorders like Parkinson’s because of its neuroprotective properties3,4.

Studies have also shown that cannabinoids interact with the endocannabinoid system’s cannabinoid receptors, CB1 and CB2, to modulate the release of dopamine.13

Research also shows that cannabis can help patients with Parkinson’s disease manage their symptoms. One study observed that after smoking cannabis, Parkinson’s disease patients saw significant improvements in motor disability and impairments, tremors, rigidity, bradykinesia, sleep, and pain 8. Additional studies have confirmed cannabis’ ability to reduce bradykinesia and tremors6,7. Most recently, a clinical trial found that cannabis significantly reduced pain and motor symptoms in Parkinson’s disease patients after 30 minutes11.

Significant improvements in well-being and quality of life scores were found in Parkinson’s disease patients that were given daily doses of CBD for one week1. One case study found that patients treated with CBD, though they didn’t see significant improvements in motor measures or general symptoms, experienced prompt and substantial reductions in the frequency of REM sleep behavior disorder events1. In one survey, despite only 4.3% of Parkinson’s disease patients responding that they used cannabis to treat their symptoms, it was ranked it as the most effective treatment option out of vitamins, prayer, massage, art therapy, music therapy and relaxation5. An anonymous questionnaire sent to patients with Parkinson’s disease found that 25 percent of 339 respondent’s had taken cannabis, with 45.9 percent of those reporting some type of benefit 14.

In addition, CBD may help with those Parkinson’s’ disease patients experiencing psychosis. Four weeks of CBD caused Parkinson’s disease patients with psychosis to experience a significant decrease in psychotic symptoms as evaluated by the Brief Psychiatric Rating Scale and the Parkinson Psychosis Questionnaire17.

Baja Hemp Co #naturallyhealing

Roxanne & Meagan

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CBD & Anxiety

Recent studies have confirmed that CBD can improve anxiety and stress in most individuals.  It has been studied in relation to:

  • Panic disorder
  • Obsessive Compulsive Disorder (OCD)
  • Social phobia
  • Post-Traumatic Stress Disorder (PTSD)
  • Generalized Anxiety Disorder (GAD)
  • Mild to moderate depression

 

5-HT1A agonist: 5-HT1A is a subtype of the serotonin receptor, which is important because anxiety and depression can sometimes be treated with medications that target the serotonin system. This is why drug companies developed selective serotonin reuptake inhibitors (SSRIs) like Prozac and Zoloft. SSRIs work by blocking reabsorption of serotonin in the brain, which increases the availability of serotonin in the synaptic space. This helps brain cells transmit more serotonin signals, which can reduce anxiety and boost mood in certain cases (although the full biological basis for this is more complicated and not fully understood).

Similar to SSRIs, CBD may boost signaling through serotonin receptors. In an animal study, Spanish researchers found that CBD enhances 5-HT1A transmission and may affect serotonin faster than SSRIs. Researchers noted:

“The fast onset of antidepressant action of CBD and the simultaneous anxiolytic (anti-anxiety) effect would solve some of the main limitations of current antidepressant therapies.”

 

Baja Hemp Co #naturallyhealing

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Studies on Alzheimer’s & CBD

Alzheimer’ s  disease is very frightening and alarming, however,  new research is hopeful. And trials have begun for dementia and Alzheimer’s disease involving CBD and the body’s receptors.

Scientists believe that there is increasing evidence that the endocannabinoid system may be regulating the neurodegenerative processes.

Dementia and Alzheimer’s are age-related dementia associated with impairments in learning and memory accompanied by neuroinflammation, oxidative stress, and neurodegeneration. 

Over the past few years, there has been a growing interest in the therapeutic potential of medications that target the endocannabinoid system (ECS).

Every day we are finding out more about the disease and how to prevent it, and possibly change the outcome. More research is becoming available with the research of CBD and this insidious disease.